Dr. Friedhelm Hildebrandt MD Boston, MA with 21+ years experience
Gender: Male Years In Practice: 21+ Phone Number:(617) 355-6129
Specialty
Pediatric Nephrology
General Pediatric Nephrology
Contact
300 Longwood Ave
561 En
Boston, MA 02115 Phone:(617) 355-6129
Insurances
Aetna Choice POS II Aetna HMO BCBS Blue Card PPO BCBS Illinois PPO BCBS Massachusetts Blue Care Elect PPO CIGNA HMO CIGNA Open Access CIGNA PPO Cofinity PPO First Health PPO
Great West PPO Harvard Pilgrim HMO Humana ChoiceCare Network PPO Multiplan PHCS PPO Multiplan PPO Tufts Health Plan PPO UniCare PPO United Healthcare - Direct Choice Plus POS United Healthcare - Direct Options PPO
Dr. Hildebrandt is an Investigator of the Howard Hughes Medical Institute and the Warren E. Grupe Professor of Pediatrics at Harvard University. He is the chief of nephrology at Boston Children’s Hospital. Dr. Hildebrandt’s work is concerned with the identification and functional characterization of recessive single-gene causes of kidney diseases in children. His group has identified over 30 novel kidney disease genes. This work implicated the primary cilium and centrosomes in nephronophthisis, thereby contributing to the identification of “ciliopathies” as a new class of human disease. Gene identification also extends to nephrotic syndrome and congenital malformations of the kidney and urinary tract. His lab studies the function of newly identified disease genes in disease models of mice and zebrafish. We developed efficient methods for gene identification using whole exome resequencing and other highly-parallel sequencing techniques. Recently, we showed that DNA damage repair plays a role in the pathogenesis of ciliopathies (Chaki et al. Cell 150:355-48, 2012; Zhou et al., Nat Genet 44:910-15, 2012).